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Accelerating radiopharmaceutical breakthroughs with high-sensitivity and high-resolution SPECT scanners for transformative research

Imaging the Future of Medicine

Our 
Story

About Us

MH3D Inc. is a medical device company developing next-generation SPECT imaging systems with unmatched sensitivity and accuracy. Our flagship technology focuses on an ultrahigh-sensitivity SPECT system designed to revolutionize the early detection and monitoring of cancer, cardiovascular, and neurodegenerative diseases.

About Us

Our History

MH3D’s roots are deeply embedded in academic excellence and industry expertise. Our technology is the culmination of over two decades of pioneering research in nuclear imaging detectors from the University of Michigan and the University of Illinois, seamlessly integrated with 20 years of real-world application in the medical imaging industry.

About us - UM
About us - UIUC

Our Mission

At MH3D, we are committed to pushing the boundaries of medical imaging to enhance diagnostic precision, empower clinicians, and improve patient outcomes worldwide.

 

Our startup is founded on a vision to revolutionize early detection of cancer, neurological disorders, and cardiovascular diseases through our pioneering nuclear imaging technology. We're committed to supporting pre-clinical and clinical research and enhancing current standards of care with high-precision tools designed for early diagnosis. 

Products

Our Product

New Alpha-Spect Mini Device
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Alpha-SPECT™ Mini

Introducing the MH3D Alpha-SPECT™ Mini, the world's first CZT-based pre-clinical SPECT system, offering features unmatched by current market options:

 

  • Unparalleled energy resolution is perfect for multi-isotope imaging.

  • An ultra-wide stationary field of view is needed for comprehensive whole-body dynamic studies of small animals.

  • Fully stationary detector system coupled to a dual-FOV micro-scanning aperture for optimized imaging resolution and ultrahigh sensitivity for a wide range of imaging applications.

  • Fully optimized multi-isotope imaging capability for studying alpha-labeled radiopharmaceuticals (alpha-RPT).

Configuration
A
-
AA
Mode
Standard Mode (A)
High Resolution Mode (A)
High-Resolution Mode (AA)
Field of View (W x L)
60mm x 80mm
40mm x 60mm
30mm x 60mm
Spatial Resolution at 140 keV
< 2.5mm
<1.5mm
< 1mm
Sensitivity
4200 cps/MBq
600 cps/MBq
Customizable
Energy Resolution at 140 keV
3-4 keV
3-4 keV
3-4 keV
Detector
CZT
CZT
CZT
Bore Size
12cm
12cm
Customizable
Reconstruction Algorithm
OSEM
OSEM
OSEM
Team

Meet the Team

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Chairman

Dr. Zhong He, PhD

Dr. Zhong He, Professor in the Department of Nuclear Engineering and Radiological Sciences at the University of Michigan, pioneered the groundbreaking 3D-readout technique, a cornerstone of semiconductor gamma-ray imaging detectors. This innovation enables exceptional energy resolution and unmatched sensitivity, transforming nuclear imaging technology.

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Chief Clinical Officer

Dr. Aileen Ouyang, PhD

Dr. Aileen Ouyang has 9 years of combined academic and industrial experience in the medical device industry. She earned her PhD in Biomedical Engineering from the University of Michigan, Ann Arbor, specializing in clinical affairs and regulatory processes.

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Senior Software Engineer

Brendan Deleon, MS

Brendan holds a master's degree in Computer Science from the University of Urbana-Champaign. He specializes in imaging processing, data processing, full-stack software development, demonstrating his expertise across multiple technical domains. a strong foundation in computer science. Brendan is committed to delivering innovative solutions that drive projects to success.

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CEO

Xiaopei Huang, MBA

Xiaopei Huang, CEO of MH3D, holds a Master of Science in Electrical Engineering from the University of Michigan and an Executive MBA from Lawrence Technological University. With a proven leadership and strategic expertise track record, she spearheads MH3D's mission to drive groundbreaking medical innovations, blending technical proficiency with visionary business acumen.

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Director of Applied Research/RSO

Dr. Jack Kuchta, PhD

Dr. Kuchta earned his PhD in Nuclear Engineering and Radiological Sciences from the University of Michigan, Ann Arbor. His team is focused on creating next-generation clinical SPECT systems to enhance clinical workflows and improve patient care outcomes.

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Software Engineer

David Paylan, MS

David is a dedicated Data Scientist who holds a Master's degree from Hopkins University. With a specialization in imaging processing and analytics, he is committed to developing software products that enhance patient outcomes. His professional expertise contributes to the advancement innovative solutions in SPECT technology.

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CTO

Dr. Ling Jian Meng, PhD

Dr. Ling-Jian Meng, Professor in the Department of Nuclear, Plasma, and Radiological Engineering at the University of Illinois at Urbana-Champaign (UIUC). His research centers on advancing emission tomography imaging technologies, focusing on revolutionizing the diagnosis and monitoring of cancer, cardiovascular diseases, and neurological disorders.

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Head of Engineering

Ansong Qin

Ansong has over 30 years of experience in software development, data processing, imaging algorithms, and production-ready system engineering. As Head of Engineering, he leads the technical development of next-generation SPECT imaging platforms.

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Upcoming Events

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European Molecular Imaging Meeting 2026

Ljubljana, Slovenia

Mar 24 - 27, 2026

Industry

Participation

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Los Angeles, California

May 30 - Jun 2, 2026

Industry Participation

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Preclinical Imaging Consortium 

Philadelphia, Pennsylvania

Apr 13 - 15, 2026

Industry Participation

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Latest News

Support

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